全国服务咨询热线:
15921799099
15921799099
简要描述：Proteus BioSciences was founded in 2002 to develop innovative products to advance proteomic research. We specialize in discovering peptides and proteins with novel biological properties
产物型号：厂商性质：经销商更新时间：2024-08-29访&苍产蝉辫;&苍产蝉辫;问&苍产蝉辫;&苍产蝉辫;量：3783详细介绍
PRODUCT #: 25-6790
| DESCRIPTION: Myosin-VIIa is one of the unconventional members of the myosin molecular motor superfamily that move along filamentous actin. The protein is expressed primarily in the inner ear, retina and testis. Defects in the myosin-VIIa gene （惭驰翱7础） are responsible for Usher syndrome, characterized by hearing impairment, lack of vestibular function and progressive retinal degeneration.MYO7A mutations are are responsible for deafness in shaker-1 mice and in other model systems. In the inner ear, myosin-VIIa is required for assembly of stereocilia, the sensory structures necessary for detecting sound signals. | |
| SPECIES CROSS-REACTIVITY: | Human, mouse, rat, pig, avian, amphibian |
| APPLICATIONS/DILUTIONS: | IF （5-10 ug/ml） |
| SOURCE: | Rabbits were immunized with amino acids 880-1077 from the tail region of human myosin-VIIa. |
| FORM/STORAGE: | 50 ug （0.5 mg/ml） of affinity purified IgG with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. |
| References: | |
| DESCRIPTION: Myosin-VIIa is one of the unconventional members of the myosin molecular motor superfamily that move along filamentous actin. The protein is expressed primarily in the inner ear, retina and testis. Defects in the myosin-VIIa gene （惭驰翱7础） are responsible for Usher syndrome, characterized by hearing impairment, lack of vestibular function and progressive retinal degeneration.MYO7A mutations are are responsible for deafness in shaker-1 mice and in other model systems. In the inner ear, myosin-VIIa is required for assembly of stereocilia, the sensory structures necessary for detecting sound signals. | |
| SPECIES CROSS-REACTIVITY: | Human, mouse, rat, pig, avian, amphibian |
| APPLICATIONS/DILUTIONS: | IF （5-10 ug/ml） WB （0.5-1.0 ug/ml） |
| SOURCE: | Rabbits were immunized with amino acids 880-1077 from the tail region of human myosin-VIIa. |
| FORM/STORAGE: | 50 ug （0.5 mg/ml） of affinity purified IgG with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. |
| References: Hasson, T. et al. （1995）, Proc. Natl. Acad. Sci. 92:9815-9819. Hasson, T. et al. （1997）, Journal of Cell Biology 137:1287-1307. Hasson, T. et al. （1997）, Cell Motil. Cytoskel. 37:127-138. Hasson, T. et al. （2005）, Cell Motil. Cytoskel. 62:13-26. | |
| DESCRIPTION: Myosin-VIIa is one of the unconventional members of the myosin molecular motor superfamily that move along filamentous actin. The protein is expressed primarily in the inner ear, retina and testis. Defects in the myosin-VIIa gene （惭驰翱7础） are responsible for Usher syndrome, characterized by hearing impairment, lack of vestibular function and progressive retinal degeneration.MYO7A mutations are are responsible for deafness in shaker-1 mice and in other model systems. In the inner ear, myosin-VIIa is required for assembly of stereocilia, the sensory structures necessary for detecting sound signals. | |
| SPECIES CROSS-REACTIVITY: | Human, mouse, rat, pig, avian, amphibian |
| APPLICATIONS/DILUTIONS: | IF （5-10 ug/ml） |
| SOURCE: | Rabbits were immunized with amino acids 880-1077 from the tail region of human myosin-VIIa. |
| FORM/STORAGE: | 50 ug （0.5 mg/ml） of affinity purified IgG with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. |
| References: | |
| DESCRIPTION: Myosin-VIIa is one of the unconventional members of the myosin molecular motor superfamily that move along filamentous actin. The protein is expressed primarily in the inner ear, retina and testis. Defects in the myosin-VIIa gene （惭驰翱7础） are responsible for Usher syndrome, characterized by hearing impairment, lack of vestibular function and progressive retinal degeneration.MYO7A mutations are are responsible for deafness in shaker-1 mice and in other model systems. In the inner ear, myosin-VIIa is required for assembly of stereocilia, the sensory structures necessary for detecting sound signals. | |
| SPECIES CROSS-REACTIVITY: | Human, mouse, rat, pig, avian, amphibian |
| APPLICATIONS/DILUTIONS: | IF （5-10 ug/ml） |
| SOURCE: | Rabbits were immunized with amino acids 880-1077 from the tail region of human myosin-VIIa. |
| FORM/STORAGE: | 50 ug （0.5 mg/ml） of affinity purified IgG with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. |
| References: | |
产物咨询
电话
蚕蚕咨询
4006551678
当前位置：
地址：上海浦东川沙镇川沙路6619号718吃瓜网
邮箱：虫蝉1蔼78产颈辞.肠辞尘
传真：021-50724961